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[4] Included on other lists of high
histamine offenders are leftovers, which makes sense given the fact that bacterial content can result in histamine production. It’s important to note that avoiding all these foods isn’t necessarily the answer for those who react negatively to histamines. So, for those who have already written down the list above, set it to the side for a second before you shun these foods from your shopping list. Why Am I So Reactive to Histamine?There are several reasons people become intolerant of or reactive to high histamine foods. Our body uses two methods to break down and metabolize histamine. Exogenous histamine refers to the histamine we ingest. Our exogenous histamine intake relies on something called DAO to metabolize it. DAO, or diamine oxidase,is the primary barrier for intestinal histamine absorption. Some of people are born with a deficiency in the production of DAO, which causes us to not be able to breakdown histamine properly. This results in
excess histamine in the body, which can wreak havoc and cause symptoms such as bloat, feeling excessively full after eating or drinking, diarrhea, abdominal pain, itchiness, hives, flushing, congestion, headache, dizziness, fast heart rate, and anxiety. Additionally, deficiencies of copper, vitamin C, and pyridoxine can also result in reduced activity of DAO.